When extubating neonates from mean airway pressures (Paw) of ≥9 cmH2O, the optimal initial pressures on high CPAP (≥9 cmH2O) remains unclear. Sometimes clinicians may choose the similar pressures (equivalent) or higher pressures on CPAP than pre-extubation mean airway pressure. 

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In this retrospective cohort study, we compared babies extubated to equivalent vs higher CPAP pressures and assessed failure of CPAP and need for re-intubation. We found that while CPAP failure was not different, the risk of re-intubation was significantly lower with use of higher pressures. 

 

Link to publication:  https://pubmed.ncbi.nlm.nih.gov/35977710/